By continuous ingestion of diatoxanthin-containing carotenoids derived from the microalgae Euglena
Confirmed research results suggesting that the rise in blood sugar level is suppressed

Euglena Co., Ltd.

　Euglena Co., Ltd. (Headquarters: Minato-ku, Tokyo, President: Mitsuru Izumo) is a diatoxanthin derived from the Euglena (Japanese name: Euglena ^{* 1} Contains carotenoids ^{* 2} We confirmed the research results suggesting that the increase in blood glucose level can be suppressed by continuous intake of.
* 1 A type of carotenoid. Included in brown algae and diatoms in addition to Euglena
* 2 A yellow to red pigment contained in animals and plants, and has been confirmed to have antioxidant effects.

■ Background and purpose
　It is said that if the blood sugar level continues to be high for a long time^{, complications such as diabetes * 3}, diabetic nephropathy ^{* 4} and diabetic retinopathy ^{* 5} are likely to occur. Therefore, by suppressing the rise in blood sugar level, it is possible to suppress the occurrence and progression of diabetes and diabetic complications.
　This time, Euglena Euglena derived diatoxanthin-containing carotenoids in a high-fat diet and a high-fat diet. I did the research to give.

■ Research content and results
　The mice were divided into three groups: (1) a group of mice fed a normal diet, (2) a group of mice fed a high-fat diet, and (3) a group of mice fed a high-fat diet containing diatoxanthin-containing carotenoids derived from Euglena After ingesting each for 6 weeks, the blood glucose level ^{* 6} was measured.
　As a result, it was found that the group of mice that ingested the high-fat diet of (3) and the diet Euglena derived diatoxanthin-containing carotenoids suppressed the increase in blood glucose level as compared with the mice that ingested only the high-fat diet of (2). confirmed. ^{* 7}

Figure: Comparison of blood sugar levels

　In other words, Euglena derived diatoxanthin-containing carotenoids may suppress the rise in blood glucose level, which is one of the causes of diabetes, and have the effect of preventing diabetes and diabetic complications and alleviating symptoms.

　The above research results were presented at the 57th Japan Oil Chemists' Society held from September 4th to 6th, 2018. In addition, we have confirmed the effect of suppressing the increase in blood glucose level of diabetic model mice by ingesting Euglena powder (http://www.euglena.jp/news/n20161031/), which is one of the active ingredients. However, this study suggests that it may be a carotenoid containing diatoxanthin.

　Going forward, we will continue to carry out research and development with the aim of utilizing the Euglena

* 3 Diabetes: A condition in which glucose is not used effectively and blood sugar (glucose) is high in the blood due to a decrease in the action of insulin, which is a hormone.
* 4 Diabetic nephropathy: One of the complications of diabetes, a condition in which waste products cannot be filtered due to the breakage of small blood vessels in the glomeruli of the kidney.
* 5 Diabetic retinopathy: One of the complications of diabetes, which may lead to bleeding and eventually vision loss due to blockage of blood vessels in the retina.
* 6 Measure blood glucose concentration
* 7 p <0.05

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Euglena Co., Ltd. Corporate Communication Division