Continued intake of the microalgae Euglena promotes the production of immunotransmitters,
Confirmed the effect suggestion that alleviates influenza symptoms

Euglena Co., Ltd.

　Euglena Co., Ltd. (Headquarters: Minato-ku, Tokyo, President: Mitsuru Izumo) is unique to microalgae Euglena (Japanese name: Euglena, hereafter Euglena) powder and Euglena. Ingestion of paramylon * 1, which is a functional component of Wovn, promotes the production of cytokine * 2, which is an immunotransmitter, and as a result, it is suggested that the effect of alleviating influenza symptoms is promoted by promoting the elimination of influenza virus. I confirmed that.

■ Background and purpose
　Influenza, which is prevalent every winter, is an acute respiratory tract infection caused by the influenza virus. When infected with the influenza virus, the human body attempts to eliminate the virus from the body by activating immune cells through the action of cytokines, which are neurotransmitters.
　Euglena powder or paramylon to influenza virus-infected mice significantly improves survival and reduces the number of influenza viruses in the lungs (2015). February 9). This time, we measured the amount of cytokines secreted in the lungs of influenza-infected mice for the purpose of elucidating the mechanism of alleviation of influenza symptoms by ingestion of Euglena

■ Research content
　Euglena powder or paramylon for 2 weeks and mice fed only diet (control group), the amount of 7 cytokines secreted in the lungs over 3 days. Was measured.

■ Results
　In the group that ate Euglena powder with meals, the amount of secretion was higher in 4 cytokines than in the control group. In addition, it was confirmed that in the group that ate paramylon with meals, the amount of secretion of 6 cytokines was significantly higher than that in the control group, and the amount of secretion of 1 cytokine was higher.
　In other words, it was suggested that pre-ingestion of Euglena powder or paramylon has the effect of alleviating influenza symptoms by activating immune cells by increasing the amount of cytokines secreted and promoting the elimination of influenza virus. ..

　The above research results were published on September 30, 2017 by Biochemical and Biophysical Research Communications (BBRC). * 3 It was published in the online version. Going forward, we will continue to carry out research and development with the aim of utilizing the Euglena
* 1 Paramylon: A polysaccharide in which glucose molecules are linearly polymerized by β-1,3-bonds.
* 2 Cytokine: A protein responsible for immune transmission in the body
* 3 Biochemical and Biophysical Research Communications (BBRC): Dutch academic journal

　The details are as follows.

Mechanism of alleviation of influenza symptoms by continuous intake of microalgae Euglena

〇Details of research content
　Three days after nasal administration of influenza virus (A / PR / 8/34 (H1N1)) to mice fed with Euglena The amount of cytokines (IL-1β, IL-6, IL-10, IL-12 (p70), TNF-α, IFN-γ, INF-β) secreted in the lungs was measured.

〇Details of results
　The group that ate Euglena powder with food showed higher levels of secretion in IL-1β, IFN-β, IFN-γ, and TNF-α compared to the control group. In addition, in the group that ate paramilon with meals, the amount of secretion was higher in IL-1β, IL-6, IL-12 (p70), IL-10, IFN-γ and TNF-α than in the control group. It increased significantly, and a high value was also confirmed in IFN-β.

〇Summary
　Euglena powder or paramylon against influenza virus (A / PR / 8/34 (H1N1)) increases the secretion of cytokines, which are immunotransmitters, mainly by the action of paramylon, and activates immune cells. As a result, it is thought that the elimination of the virus was promoted and the effect of alleviating influenza symptoms was suggested.

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